BDBM50617991 CHEMBL5437643

SMILES [H][C@]1(C[C@H](O)[C@H](C)[C@@H](O1)\C=C\C)[C@@H](N)\C=C\C=C(/C)C[C@@H](C)\C=C(\C)/C=C/[C@H](O)C[C@H](N)CC(=O)OC

InChI Key InChIKey=PLLUXUKFSITXBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617991   

TargetExportin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617991(CHEMBL5437643)
Affinity DataIC50: 340nMAssay Description:Inhibition of CRM1-mediated nuclear export in human HeLa cells expressing mCherry-tagged NES reporter incubated for 3 hrs by confocal microscopy anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetExportin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617991(CHEMBL5437643)
Affinity DataIC50: 550nMAssay Description:Inhibition of CRM1 nuclear export in human HeLa cells assessed as CRM1 depletion measured after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed