BDBM50617540 CHEMBL5403837

SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(CNC(=N)c2ccccc2)cc1

InChI Key InChIKey=KKECIKPWQGPKEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617540   

TargetNitric oxide synthase, inducible(Human)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50617540(CHEMBL5403837)
Affinity DataIC50: 832nMAssay Description:Inhibition of N-terminal his6-tagged recombinant human iNOS expressed in Escherichia coli preincubated for 15 mins followed by NADPH addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50617540(CHEMBL5403837)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal his-tagged bovine eNOS (2 to 1205 residues) expressed in Escherichia coli preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed