BDBM50617539 CHEMBL5396622

SMILES Cc1ccc(cc1)S(=O)(=O)NCc1cccc(CNC(=N)c2ccccc2)c1

InChI Key InChIKey=APXSFESQCMJVLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617539   

TargetNitric oxide synthase, inducible(Human)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50617539(CHEMBL5396622)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal his6-tagged recombinant human iNOS expressed in Escherichia coli preincubated for 15 mins followed by NADPH addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50617539(CHEMBL5396622)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal his-tagged bovine eNOS (2 to 1205 residues) expressed in Escherichia coli preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed