BDBM50617439 CHEMBL5432177

SMILES Nc1cc(C(F)F)c(cn1)-c1nc(nc(n1)N1CCCCC1)C1CCOCC1

InChI Key InChIKey=XLHGPALQKMSBLS-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617439   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50617439(CHEMBL5432177)Copy SMILESCopy InChI

Affinity DataKi:  1.38E+3nMAssay Description:Displacement of Alexa fluor 647-labeled kinase tracer 314 from recombinant N-terminal (His)6-tagged p110alpha (unknown origin) assessed as inhibition...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2024
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50617439(CHEMBL5432177)Copy SMILESCopy InChI

Affinity DataKi:  5.86E+3nMAssay Description:Displacement of Alexa fluor 647-labeled kinase tracer 314 from N-terminal GST-fused truncated recombinant human mTOR (1360 to 2549 residues) assessed...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL