BDBM50617422 CHEMBL5437258

SMILES Nc1ncc(-c2nc(nc(n2)C2=CCOCC2)N2CCOCC2)c(n1)C(F)F

InChI Key InChIKey=VRLWAVVAMANIIJ-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617422   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50617422(CHEMBL5437258)Copy SMILESCopy InChI

Affinity DataKi:  8.10nMAssay Description:Displacement of Alexa fluor 647-labeled kinase tracer 314 from recombinant N-terminal (His)6-tagged p110alpha (unknown origin) assessed as inhibition...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50617422(CHEMBL5437258)Copy SMILESCopy InChI

Affinity DataKi:  422nMAssay Description:Displacement of Alexa fluor 647-labeled kinase tracer 314 from N-terminal GST-fused truncated recombinant human mTOR (1360 to 2549 residues) assessed...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL