BDBM50617252 CHEMBL5435260

SMILES C[C@H](c1ccccc1)n1nnc2cnc3ccc(cc3c12)-c1ccc(OCCCN(C)C)nc1

InChI Key InChIKey=KAHMZYOZNYFPKN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50617252   

TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617252(CHEMBL5435260)
Affinity DataIC50: 1nMAssay Description:Inhibition of ATM (unknown origin) using GST-cMyc-p53 as substrate incubated for 30 mins in presence of Mg/ATP mix by HTRF-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617252(CHEMBL5435260)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3K p110 alpha/p85 alpha using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 30 mins in the presence of Mg/A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617252(CHEMBL5435260)
Affinity DataIC50: 216nMAssay Description:Inhibition of mTOR (unknown origin) incubated for 40 mins in the presence of Mn/ATP mix by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617252(CHEMBL5435260)
Affinity DataIC50: 123nMAssay Description:Inhibition of DNA-PK (unknown origin) using GST-cMyc-p53 as substrate incubated for 30 mins in the presence of Mg/ATP mix by HTRF-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617252(CHEMBL5435260)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ATR (unknown origin) using GST-cMyc-p53 as substrate incubated for 30 mins in the presence of Mg/ATP mix by HTRF-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617252(CHEMBL5435260)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of human PI3K p110 beta/p85 alpha using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 30 mins in the presence of Mg/AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50617252(CHEMBL5435260)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3K p120 gamma using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 30 mins in the presence of Mg/ATP mix by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617252(CHEMBL5435260)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human PI3K p110 delta/p85 alpha using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 30 mins in the presence of Mg/A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed