BDBM50617218 CHEMBL5425065

SMILES [H][C@@]12CN(C(=O)c3ccccc3)[C@@]([H])(C1)C(=O)NC(Cc1cn(CC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)NC[C@H](C(C)C)C(=O)N[C@@H](Cc3cccc(c3)C(F)(F)F)C(=O)N2)nn1)C(N)=O

InChI Key InChIKey=ZAPBZKBLKRCOOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50617218   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617218(CHEMBL5425065)
Affinity DataIC50: 90nMAssay Description:Displacement of FAM labeled p53 fragment from human MDM2 (1 to 116 residues) incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed