BDBM50617215 CHEMBL5395151

SMILES [H][C@@]12CN(C(=O)c3ccccc3)[C@@]([H])(C1)C(=O)N[C@@H](Cc1cn(CC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](Cc3ccccc3)C(=O)NCC(=O)NC[C@H](C(C)C)C(=O)N[C@@H](Cc3cccc(c3)C(F)(F)F)C(=O)N2)nn1)C(N)=O

InChI Key InChIKey=ZAPBZKBLKRCOOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617215   

TargetProtein Mdm4(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617215(CHEMBL5395151)
Affinity DataIC50: 43nMAssay Description:Inhibition of human MDM4 (1 to 116 residues) incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617215(CHEMBL5395151)
Affinity DataIC50: 43nMAssay Description:Inhibition of human MDM2 incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed