BDBM50617134 CHEMBL5413230

SMILES Cc1cccc(C[C@H](NC(=O)c2ccc(F)cc2)C(=O)N[C@@H](CCCn2cc(CC(O)=O)nn2)C#N)c1

InChI Key InChIKey=ZFFNUUKPQOVZQL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50617134   

TargetCathepsin S(Human)
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50617134(CHEMBL5413230)
Affinity DataKi:  320nMAssay Description:Inhibition of human cathepsin S using Z-VVR-AMC as substrate preincubated for 20 mins followed by pre-activated enzyme addition and measured after 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProcathepsin L(Human)
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50617134(CHEMBL5413230)
Affinity DataKi:  540nMAssay Description:Inhibition of human cathepsin L using Z-FR-AMC as substrate preincubated for 20 mins followed by pre-activated enzyme addition and measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCathepsin B(Human)
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50617134(CHEMBL5413230)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of human cathepsin B using Z-RR-AMC as substrate assessed as inhibition constant preincubated for 20 mins followed by pre-activated enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCathepsin K(Human)
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50617134(CHEMBL5413230)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human cathepsin K using Z-LR-AMC as substrate preincubated for 20 mins followed by pre-activated enzyme addition and measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed