BDBM50617128 CHEMBL5436581

SMILES C[C@H]1CN(C[C@H]1Nc1nccc(n1)-c1c(nn2ccccc12)-c1ccccc1)C(=O)c1ccc(NC(=O)CCCN(C)C)cc1

InChI Key InChIKey=KHBKMPDJKIORDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617128   

TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617128(CHEMBL5436581)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Nano-Luc fused JNK2 (unknown origin) expressed in HEK293T cells pretreated for 3 hrs followed by K5-tarcer addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617128(CHEMBL5436581)
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged human recombinant p38alpha expressed in Escherichia coli by Lanthascreen Binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed