BDBM50617122 CHEMBL5398275

SMILES C[C@@H]1CN(C[C@H]1Nc1nccc(n1)-c1c(nn2ccccc12)-c1ccccc1)C(=O)c1ccc(NC(=O)\C=C\CN(C)C)cc1

InChI Key InChIKey=FVONQZQMUHLATI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617122   

TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617122(CHEMBL5398275)
Affinity DataIC50: 160nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617122(CHEMBL5398275)
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed