BDBM50617104 CHEMBL5395724

SMILES COc1cc(cc(OC)c1OC)-c1nc2ccccc2c2nc3ccccn3c12

InChI Key InChIKey=XAYLYDCVXNGOTL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50617104   

TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617104(CHEMBL5395724)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617104(CHEMBL5395724)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of recombinant Top1 in Leishmania donovani Ag83 whole cell extract assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617104(CHEMBL5395724)
Affinity DataIC50: 8.75E+3nMAssay Description:Inhibition of recombinant Top1 in Antimony resistant Leishmania donovani BHU575 whole cell extract assessed as relaxation of supercoiled pBluescript ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed