BDBM50617086 CHEMBL5398727

SMILES CN1C(C(=O)NN)C(=O)N(C)c2ccccc12

InChI Key InChIKey=OIBQGCOMEWUAJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617086   

TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50617086(CHEMBL5398727)
Affinity DataIC50: 100nMAssay Description:Inhibition of wild type EGFR (unknown origin) preincubated for 5 mins followed by substrate and ATP addition and further incubated for 30 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50617086(CHEMBL5398727)
Affinity DataIC50: 4.02E+3nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by substrate and ATP addition and further incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed