BDBM50617053 CHEMBL5437282::US20250129048, Example 2

SMILES COc1cc([C@@H](C)C(=O)N2CC[C@@H](C2)Nc2ccc(-c3nc(n(C)n3)C(F)(F)F)c(C)n2)c(F)cn1

InChI Key InChIKey=ULQWRELSYOPZMD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617053   

TargetMelanocortin receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50617053(CHEMBL5437282 | US20250129048, Example 2)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity at human MC4R in CHO cells measured for 24 hrs in presence of alpha-MSHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50617053(CHEMBL5437282 | US20250129048, Example 2)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent