BDBM50616944 CHEMBL5398151

SMILES CNC(=O)CCc1ccc(cc1)C(=O)NCc1cccc(c1)N1CCN(CC1)c1nc(Nc2cccc(c2)S(N)(=O)=O)ncc1OC

InChI Key InChIKey=HSNLCCKRVCPONE-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50616944   

TargetBone morphogenetic protein receptor type-2(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50616944(CHEMBL5398151)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta by LanthaScreen TR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50616944(CHEMBL5398151)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ACVRL1 (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50616944(CHEMBL5398151)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ACVR1 (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50616944(CHEMBL5398151)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed