BDBM50616853 CHEMBL5413031

SMILES CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1cc(NC(=O)CC)ccc1C

InChI Key InChIKey=RGDLBJLVOAQVAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50616853   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50616853(CHEMBL5413031)
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLlSA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50616853(CHEMBL5413031)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of EZH2 methyltransferase activity in human A2780 cells assessed as reduction in H3K27me3 level incubated for 3 days by Western blot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed