BDBM50616732 CHEMBL5415704

SMILES CC#CC(=O)NC12CC(C1)(C2)NC1=C(Cl)C(=O)c2cccnc2C1=O

InChI Key InChIKey=UYIRPHWBVZGXIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50616732   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50616732(CHEMBL5415704)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human NSD2 (941 to 1240 residues) using SAM as substrate incubated for 3 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50616732(CHEMBL5415704)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of EZH2 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition and measured after 4 hrs by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed