BDBM50616676 CHEMBL5402262

SMILES CC(C)(NC(=O)O[C@@H]1CN2CCC1CC2)c1csc(n1)-c1ccc(Cl)c(O)c1

InChI Key InChIKey=UUBPVUULNCOTKK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50616676   

TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50616676(CHEMBL5402262)
Affinity DataIC50: 110nMAssay Description:Inhibition of N-terminal 6-his tagged TEV fused full length human NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-Codonplus(DE3)-RIL cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50616676(CHEMBL5402262)
Affinity DataIC50: 300nMAssay Description:Inhibition of NTMT1 in HEK293 cells assessed as reduction in me3-RCC1 level incubated for 3 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50616676(CHEMBL5402262)
Affinity DataIC50: 300nMAssay Description:Inhibition of NTMT1 in HEK293 cells assessed as reduction in me3-SET level incubated for 3 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed