BDBM50616388 CHEMBL5413121

SMILES CC[C@H](C)[C@H](N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCN)NC(=O)CC[C@@H](NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1)C(O)=O)C(=O)NCCCCCC(N)=O

InChI Key InChIKey=AVXZGSSHGFLSMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50616388   

Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50616388(CHEMBL5413121)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 10 to 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50616388(CHEMBL5413121)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant MMP12 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 10 to 15 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50616388(CHEMBL5413121)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant MMP13 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 10 to 15 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed