BDBM50616339 CHEMBL5405329

SMILES COC(=O)C(=C\c1cn(CC(=O)Nc2cccc(OC)c2)c2ccccc12)\C#N

InChI Key InChIKey=GOQXHMPUSQNADT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50616339   

TargetMonocarboxylate transporter 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616339(CHEMBL5405329)
Affinity DataIC50: 105nMAssay Description:Inhibition of MCT1 transport activity in human A549 cells using 3-BP as substrate assessed as reduction in intracellular 3-BP level by measuring incr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616339(CHEMBL5405329)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells incubated for 30 mins by calcein AM dye based fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50616339(CHEMBL5405329)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells incubated for 180 mins by daunorubicin based fluorescence flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed