BDBM50616143 CHEMBL5439514

SMILES CCNC(=O)c1ccc2n(C3CCN(C[C@@H](O)c4ccc(Cl)cc4)CC3)c(=O)[nH]c2c1

InChI Key InChIKey=URDWEWAPLOEYQL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50616143   

TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616143(CHEMBL5439514)
Affinity DataKi:  540nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProtein ENL(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616143(CHEMBL5439514)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to human his-tagged recombinant YEATS1 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616143(CHEMBL5439514)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity to human his-tagged recombinant YEATS3 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616143(CHEMBL5439514)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of hERG assessed as inhibition constant by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetYEATS domain-containing protein 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616143(CHEMBL5439514)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity to human his-tagged recombinant YEATS2 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed