BDBM50616118 CHEMBL5421995

SMILES O=C(NC12CC3CC(CC(C3)C1)C2)c1ccccc1OCc1ccccc1

InChI Key

Data  2 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50616118   

TargetFatty-acid amide hydrolase 1(Human)
University Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50616118(CHEMBL5421995)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human FAAH using AMC-AA as substrate preincubated for 10 mins followed by substrate addition measured after 2 hrs by fluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50616118(CHEMBL5421995)
Affinity DataEC50:  124nMAssay Description:Agonist activity at human CB2 receptor overexpressed in CHO-K1 cells assessed as cAMP level incubated for 30 mins by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Mouse)
University Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50616118(CHEMBL5421995)
Affinity DataEC50:  52nMAssay Description:Agonist activity at mouse CB2 receptor transfected in CHO-K1 cells assessed as beta2-arrestin recruitment incubated for 90 mins by luminescence based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50616118(CHEMBL5421995)
Affinity DataEC50:  489nMAssay Description:Binding affinity to human CB1 receptor in CHO cells incubated for 15 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50616118(CHEMBL5421995)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in HEK293 cell membrane incubated for 90 mins by beta scintillation counter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50616118(CHEMBL5421995)
Affinity DataKi:  241nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in HEK293 cell membrane incubated for 90 mins by beta scintillation counter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed