BDBM50616104 CHEMBL5428186

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)C)C(=O)N[C@@H](C)C(=O)C(=O)NCCCCc1ccccc1

InChI Key InChIKey=CSOZBEDEUIULQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50616104   

TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science

Curated by ChEMBL
LigandPNGBDBM50616104(CHEMBL5428186)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant C-terminal hexahistidine tagged mature human PARL using Ac-RRRAVFLA-4mc as substrate preincubated for 1 hr followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Science

Curated by ChEMBL
LigandPNGBDBM50616104(CHEMBL5428186)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of tetracycline inducible FLAG tagged human PARL expressed in human PARL knockout Flp-In-T-REx-293 cells cotransfected human PGAM5-Myc ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed