BDBM50615898 CHEMBL5276362

SMILES O[C@H]1CCCN(C1)C(=O)c1cccc(c1)-c1n[nH]c2ncc(Cc3cc(F)ccc3F)cc12

InChI Key InChIKey=JRLOPMVTMMPZMV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50615898   

TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50615898(CHEMBL5276362)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50615898(CHEMBL5276362)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of PLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50615898(CHEMBL5276362)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50615898(CHEMBL5276362)
Affinity DataIC50: 76nMAssay Description:Inhibition of TRKC (unknown origin) using TK as substrate in presence of ATP incubated for 40 mins by HTRF KinEASE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50615898(CHEMBL5276362)
Affinity DataIC50: 26nMAssay Description:Inhibition of TRKA (unknown origin) using TK as substrate in presence of ATP incubated for 30 mins by HTRF KinEASE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50615898(CHEMBL5276362)
Affinity DataIC50: 118nMAssay Description:Inhibition of TRKB (unknown origin) using TK as substrate in presence of ATP incubated for 40 mins by HTRF KinEASE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed