BDBM50615868 CHEMBL5285661

SMILES Oc1nc(sc1C(=O)N1CCCO1)-c1cccc(F)c1

InChI Key InChIKey=LVRUKRLHASLAAP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615868   

LigandPNGBDBM50615868(CHEMBL5285661)
Affinity DataIC50: 16nMAssay Description:Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in ethyl 4-methoxy-2-phenylthiazole-5-carboxylate induced Ca2+ efflux prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
LigandPNGBDBM50615868(CHEMBL5285661)
Affinity DataIC50: 17nMAssay Description:Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in icilin induced Ca2+ efflux preincubated for 5 mins followed by icilin ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
LigandPNGBDBM50615868(CHEMBL5285661)
Affinity DataIC50: 12nMAssay Description:Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in cold stimulated Ca2+ efflux preincubated for 5 mins followed by cold sti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed