BDBM50615673 CHEMBL5282787

SMILES CNC(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@]3([C@H]2c2cccc(Cl)c2F)C(=O)Nc2cc(Cl)ccc32)cc1

InChI Key InChIKey=NAFGFZPKKDOIBX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50615673   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50615673(CHEMBL5282787)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to recombinant human MDM2 (1 to 118 residues) assessed as inhibition constant using FAM-tagged p-53 based peptide as substrate by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed