BDBM50615495 CHEMBL5287304

SMILES O=C(N1CCN(CC1)c1ncnc2c(C#N)c3CCCCCn3c12)c1ccco1

InChI Key InChIKey=WMHPTFSUJWBSCV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615495   

TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50615495(CHEMBL5287304)Copy SMILESCopy InChI

Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of MRP1 in human NCI-H69AR cells incubated for 180 mins in presence of daunorubicin by flow cytometry analysisMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50615495(CHEMBL5287304)Copy SMILESCopy InChI

Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of BCRP (unknown origin) expressed in dog MDCK-II cells using pheophorbide A as substrate preincubated for 20 mins followed by substrate a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/23/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL