BDBM50615490 CHEMBL5266836

SMILES CCn1cc(C#N)c2ncnc(N3CCN(CCc4c[nH]c5ccccc45)CC3)c12

InChI Key InChIKey=QDQQSLWAFLBLAP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615490   

TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50615490(CHEMBL5266836)Copy SMILESCopy InChI

Affinity DataIC50: 855nMAssay Description:Inhibition of MRP1 in human NCI-H69AR cells incubated for 180 mins in presence of daunorubicin by flow cytometry analysisMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50615490(CHEMBL5266836)Copy SMILESCopy InChI

Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of BCRP (unknown origin) expressed in dog MDCK-II cells using pheophorbide A as substrate preincubated for 20 mins followed by substrate a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/23/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL