BDBM50615482 CHEMBL5279701

SMILES C(Cc1ccccc1)N1CCN(CC1)c1ncnc2c3ccccc3[nH]c12

InChI Key InChIKey=WSQDGWOFRGACTF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615482   

TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50615482(CHEMBL5279701)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of P-gp (unknown origin) incubated for 30 mins by calcein AM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50615482(CHEMBL5279701)
Affinity DataIC50: 405nMAssay Description:Inhibition of MRP1 in human NCI-H69AR cells incubated for 180 mins in presence of daunorubicin by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
LigandPNGBDBM50615482(CHEMBL5279701)
Affinity DataIC50: 839nMAssay Description:Inhibition of BCRP (unknown origin) expressed in dog MDCK-II cells using pheophorbide A as substrate preincubated for 20 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed