BDBM50615468 CHEMBL5288378

SMILES COc1ccc(\C=C\C(=O)c2ccccc2NC(=O)c2cnc3ccccc3c2)cc1OC

InChI Key InChIKey=HBGPQWXCRVPJIS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615468   

TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50615468(CHEMBL5288378)Copy SMILESCopy InChI

Affinity DataIC50: 494nMAssay Description:Inhibition of P-gp (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/23/2024
Entry Details
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50615468(CHEMBL5288378)Copy SMILESCopy InChI

Affinity DataIC50: 573nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 60 mins by Hoechst 33342...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/23/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL