BDBM50615000 CHEMBL5277819

SMILES [H][C@@]12CCN(C[C@]1([H])[C@@]2(CN)c1ccsc1)c1cnc2c(n[nH]c2n1)-c1cccnc1C(F)(F)F

InChI Key InChIKey=UMXCSQLOVDOKCZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615000   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
IRBM

Curated by ChEMBL

LigandBDBM50615000(CHEMBL5277819)Copy SMILESCopy InChI

Affinity DataIC50: 34nMAssay Description:Allosteric inhibition of recombinant human SHP2 using IRS1 peptide and DiFMUP as substrate incubated for 30 mins followed by DiFMUP addition and meas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
IRBM

Curated by ChEMBL

LigandBDBM50615000(CHEMBL5277819)Copy SMILESCopy InChI

Affinity DataIC50: 5.56E+3nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL