BDBM50614989 CHEMBL5290376

SMILES [H][C@@]12CCN(C[C@]1([H])[C@@]2(CN)c1ccccc1)c1cnc(Sc2cccnc2C(F)(F)F)c(N)n1

InChI Key InChIKey=DOJYBVBLGGSLJG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50614989   

LigandPNGBDBM50614989(CHEMBL5290376)
Affinity DataIC50: 360nMAssay Description:Allosteric inhibition of recombinant human SHP2 using IRS1 peptide and DiFMUP as substrate incubated for 30 mins followed by DiFMUP addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed