BDBM50614870 CHEMBL5284765

SMILES C[C@H]1Nc2ccc3ncc(C(=O)NC(C)(C)COc4ccc(F)cc14)n3n2

InChI Key InChIKey=MNXGNEBABBRZPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614870   

TargetALK tyrosine kinase receptor(Human)
Shanghai Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50614870(CHEMBL5284765)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of wild type ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghai Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50614870(CHEMBL5284765)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed