BDBM50614708 CHEMBL5272014

SMILES Cc1ccc(NC(=O)Nc2cc(cc3C(C=CCOc23)c2ccccc2)-c2ccccc2-c2nn[nH]n2)cc1

InChI Key InChIKey=ROPDQICAVLKEAY-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50614708   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614708(CHEMBL5272014)
Affinity DataIC50: 11nMAssay Description:Inhibition of IDO1 (unknown origin) expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614708(CHEMBL5272014)
Affinity DataEC50:  7.80E+4nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614708(CHEMBL5272014)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614708(CHEMBL5272014)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed