BDBM50614705 CHEMBL5287356

SMILES Cc1ccc(NC(=O)Nc2cc(cc3[C@H](c4ccccc4)C(C)(C)Oc23)-c2ccccc2-c2nn[nH]n2)cc1

InChI Key InChIKey=VJVHZGPGBNUIKD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50614705   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614705(CHEMBL5287356)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of IDO1 (unknown origin) expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614705(CHEMBL5287356)
Affinity DataEC50:  1.50E+4nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614705(CHEMBL5287356)
Affinity DataIC50: 420nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed