BDBM50614535 CHEMBL5271284

SMILES Cc1cc(Oc2ccccc2)ccc1-c1nn([C@H]2CCCN(C2)C(=O)C=C)c2ncnc(N)c12

InChI Key InChIKey=BJMXICGJKUALLN-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50614535   

TargetTyrosine-protein kinase BTK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 109nMAssay Description:Covalent inhibition of NanoLuc fused BTK (unknown origin) expressed in HEK293 cells incubated for 90 mins by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of BTK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BLK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BMX (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 344nMAssay Description:Inhibition of ITK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 197nMAssay Description:Inhibition of EGFR (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase HCK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 30nMAssay Description:Inhibition of HCK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 874nMAssay Description:Inhibition of JAK3 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 34nMAssay Description:Inhibition of SRC (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed