BDBM50614533 CHEMBL5267053

SMILES O=C1N[C@H]2C[C@@H](C2)OCc2cccc(Nc3cc([nH]n3)[C@H]3CC[C@H](C3)O1)n2

InChI Key InChIKey=LAQCQSKKZIRXFW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50614533   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tencent Ai Lab

Curated by ChEMBL
LigandPNGBDBM50614533(CHEMBL5267053)
Affinity DataIC50: 370nMAssay Description:Inhibition of CDK2/Cyclin E1 (unknown origin) assessed as inhibition of substrate peptide phosphorylation using eIF4E-binding protein 1 as peptide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tencent Ai Lab

Curated by ChEMBL
LigandPNGBDBM50614533(CHEMBL5267053)
Affinity DataIC50: 45nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tencent Ai Lab

Curated by ChEMBL
LigandPNGBDBM50614533(CHEMBL5267053)
Affinity DataIC50: 34nMAssay Description:Inhibition of CDK6/Cyclin D3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tencent Ai Lab

Curated by ChEMBL
LigandPNGBDBM50614533(CHEMBL5267053)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) assessed as inhibition of substrate peptide phosphorylation using MBP as peptide substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Tencent Ai Lab

Curated by ChEMBL
LigandPNGBDBM50614533(CHEMBL5267053)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of GSK3beta (unknown origin) assessed as inhibition of substrate peptide phosphorylation using eIF4E-binding protein 1 as peptide substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed