BDBM50614502 CHEMBL5284513

SMILES CC1CN(C)C(=O)CN1c1ncc2[nH]nc(-c3cnn(C)c3)c2n1

InChI Key InChIKey=PTGSNZODFVWKQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614502   

TargetFibroblast growth factor receptor 3(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50614502(CHEMBL5284513)
Affinity DataIC50: 281nMAssay Description:Inhibition of recombinant N-terminal His-Avi-tag human FGFR3 (447 to 761 residues) expressed in Sf9 infected baculovirus expression system using biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50614502(CHEMBL5284513)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant human wild type FGFR1 (399 to 820 residues) using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed