BDBM50614391 CHEMBL4642983

SMILES COc1cccc(c1)-c1nn(cc1-c1ccnc(NCCCNC(=O)Nc2ccc(Cl)c(Cl)c2)c1)-c1ccccc1

InChI Key InChIKey=NLBSIZDYPZEHPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614391   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50614391(CHEMBL4642983)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of RAF1 (unknown origin) using magnesium acetate as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50614391(CHEMBL4642983)
Affinity DataIC50: 770nMAssay Description:Inhibition of B-RAF V600E mutant (unknown origin) using magnesium acetate as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed