BDBM50614317 CHEMBL5281208

SMILES O=C(OCC1CCCO1)c1cccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)c1

InChI Key InChIKey=MSDPZTKHHNBQPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614317   

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50614317(CHEMBL5281208)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin) using 33P-ATP as substrate and measured after 120 mins by radiometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Rat)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50614317(CHEMBL5281208)
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK2 in rat A7R5 cells assessed as MLC phosphorylation at T18/S19 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed