BDBM50614299 CHEMBL5281033

SMILES Clc1ccccc1CC(=O)Nc1ccc(cc1OCCN1CCCC1)-c1cn[nH]c1

InChI Key InChIKey=QZFJGJOKFAXJGE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50614299   

TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50614299(CHEMBL5281033)
Affinity DataIC50: 9nMAssay Description:Inhibition of ROCK2 (unknown origin) using FITC-AHA- AKRRRLSSLRA-OH as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50614299(CHEMBL5281033)
Affinity DataIC50: 111nMAssay Description:Inhibition of ROCK1 (unknown origin) using FITC-AHA- AKRRRLSSLRA-OH as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50614299(CHEMBL5281033)
Affinity DataIC50: 9nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50614299(CHEMBL5281033)
Affinity DataIC50: 111nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed