BDBM50614156 CHEMBL5280735

SMILES [2H]C([2H])(Oc1nc2CN(CCc2c(n1)N1CC2CCC(C1)N2)c1cc(O)cc(Cl)c1C(F)(F)F)C12CCCN1CCC2

InChI Key InChIKey=XSIWFZYGPJBTKA-BPPAMHLBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50614156   

TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50614156(CHEMBL5280735)
Affinity DataIC50: 50nMAssay Description:Inhibition of GTP bound KRAS G12D mutant in human GP2d cells assessed as reduction in pERK level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed