BDBM50614137 CHEMBL5281673

SMILES O=C1CC2Cc3ccsc3C2=NN1CCCCCCCN1CCN(Cc2cccc3n(ccc23)S(=O)(=O)c2ccccc2)CC1

InChI Key InChIKey=UHZOUSUGNFTACG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50614137   

TargetAcetylcholinesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614137(CHEMBL5281673)
Affinity DataIC50: 7.18E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614137(CHEMBL5281673)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614137(CHEMBL5281673)
Affinity DataKi:  3.76E+3nMAssay Description:Displacement of [3H]SB269970 from human 5-HT7 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614137(CHEMBL5281673)
Affinity DataKi:  6.62E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK cell membrane incubated for 120 mins by microplate beta scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed