BDBM50614128 CHEMBL5281228

SMILES CC(=O)N1CCC(C)(c2ccccc2)c2cc(NC(=O)CCc3cccc(c3)C(F)(F)F)ccc12

InChI Key InChIKey=IOEFWCOWBKDSQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614128   

TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandPNGBDBM50614128(CHEMBL5281228)
Affinity DataIC50: 11nMAssay Description:Allosteric antagonist activity at human TSHR expressed in CHO cells assessed as inhibition of bTSH-induced cAMP production incubated for 2 hrs by lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFollicle-stimulating hormone receptor(Human)
Byondis

Curated by ChEMBL
LigandPNGBDBM50614128(CHEMBL5281228)
Affinity DataIC50: 17nMAssay Description:Allosteric antagonist activity at human FSHR expressed in CHO cells assessed as inhibition of FSH-induced activity incubated for 4 hrs by CRE-lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed