BDBM50614101 CHEMBL297116

SMILES Nc1ccc2CN(C3CCC(=O)NC3=O)C(=O)c2c1

InChI Key InChIKey=LAGNQECGHYBSCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50614101   

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50614101(CHEMBL297116 | US20250127903, Compound 307)
Affinity DataIC50: 658nMAssay Description:Displacement of fluorescent tracer from NanoLuc-tagged CRBN (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM50614101(CHEMBL297116 | US20250127903, Compound 307)
Affinity DataKd: <1.00E+4nMAssay Description:Measuring compound ligand binding to CRBN-DDB1 was carried out using an established sensitive and quantitative in vitro fluorescence polarization (FP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent