BDBM50613978 CHEMBL5286565

SMILES [2H]C([2H])([2H])NC(=O)c1nnc(NC(=O)C2CC2)cc1Nc1cccc(C(=O)Nc2ccc(cc2)C2CCCNC2=O)c1OC

InChI Key InChIKey=VARDNFBNQCTKJB-FIBGUPNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50613978   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nanjing University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50613978(CHEMBL5286565)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of TYK2 dependent IFNalpha-stimulated STAT3 phosphorylation in human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed