BDBM50613905 CHEMBL5289293

SMILES Cc1cccc(n1)-c1[nH]c(NCc2ccc(F)c(F)c2)nc1-c1ccc2n(C)ncc2c1

InChI Key InChIKey=ZJWPVDDUMUELBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50613905   

TargetTGF-beta receptor type-1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613905(CHEMBL5289293)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of ALK5 in human Hs-578T cells assessed as effect of TGF-beta-induced Smad3/4 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed