BDBM50613898 CHEMBL5283753

SMILES Cc1cccc(n1)-c1[nH]c(NCc2cccc(F)c2)nc1-c1ccc2n(C)ncc2c1

InChI Key InChIKey=QYMHHIWJCCQYPU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50613898   

TargetTGF-beta receptor type-1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK5 in human Hs-578T cells assessed as effect of TGF-beta-induced Smad3/4 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of ALK5 in human Hs-578T cells assessed as effect of TGF-beta-induced Smad3/4 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ALK2 by NanoBERT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Mouse)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of mouse CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Mouse)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613898(CHEMBL5283753)
Affinity DataIC50: 7.15E+4nMAssay Description:Inhibition of mouse CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed