BDBM50613890 CHEMBL5284872

SMILES Cc1nn2CCCc2c1C1CCN(C[C@H]2CN(CC3(CCCC3)C(O)=O)C[C@@H]2c2cc(F)cc(F)c2)CC1

InChI Key InChIKey=TVSDIXMZHFZVGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613890   

TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50613890(CHEMBL5284872)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50613890(CHEMBL5284872)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed