BDBM50613888 CHEMBL5279229

SMILES CCc1nn(CC2CC2)c(C)c1C1CCN(C[C@H]2CN(CC3(CC4CC4C3)C(O)=O)C[C@@H]2c2cccc(F)c2)CC1

InChI Key InChIKey=POFJJAROYFMIIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613888   

TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50613888(CHEMBL5279229)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Arginase I (unknown origin) assessed as L-ornithine formation by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50613888(CHEMBL5279229)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Arginase I (unknown origin) by ThioOrnithine Generating enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed